Florence is one of those cities that completely sweeps you off your feet – whether it’s your first visit or your fifth. The cobblestone streets, Renaissance architecture, and that magical golden-hour glow over the Arno River? Absolutely dreamy. But here’s the thing: where you stay can make or break your experience.
Each neighborhood in Florence has its own personality, and if you just book the first hotel you find near the Duomo, you might be missing out on something way more special. Some areas are buzzing with tourists, while others have a more local, artsy feel. Some are perfect for foodies and nightlife lovers, while others are better if you’re on a budget or want to wake up to postcard-worthy views.
That’s why I’ve put together this guide – to help you find the perfect place to stay based on your travel style. Whether you’re looking for a boutique hotel in the heart of the action or a charming Airbnb in a quieter part of town, Florence has something for everyone. Let’s dive into the best areas to stay in Florence and some top hotel picks that will make your trip unforgettable!
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Centro Storico (Historic Center) – Best for First-Timers
If it’s your first time in Florence, staying in Centro Storico is a no-brainer. This is the heart of the city, where you’ll be within walking distance of major landmarks like the Duomo, Ponte Vecchio, Piazza della Signoria, and Uffizi Gallery. Waking up in the morning and stepping right into Florence’s postcard-perfect streets is an experience in itself.
Of course, staying here means you’ll be in the most touristy part of the city, and prices tend to be higher. But if you want to soak up Florence’s magic without needing taxis or public transport, it’s worth it!
Top Hotels in Centro Storico:
- Hotel Brunelleschi – A stunning boutique hotel with Duomo views, set in a medieval tower.
- Palazzo Niccolini al Duomo – Stay in an actual palace just steps from the Duomo!
- FH55 Hotel Calzaiuoli – Modern comfort in the heart of the city, just a short walk from all the attractions.

Oltrarno – Best for a Local & Artsy Vibe
Cross the river, and you’ll find yourself in Oltrarno, a neighborhood that feels more local and relaxed than the busy historic center. This area is known for its art studios, hidden cafés, and artisan workshops, making it perfect for those who love a creative, bohemian vibe.
One of my favorite things to do in Oltrarno is just wandering through the charming streets, stopping for an aperitivo in Piazza Santo Spirito or visiting Palazzo Pitti and the Boboli Gardens. It’s the kind of place where you can experience Florence at a slower pace, away from the crowds.
Top Hotels in Oltrarno:
- AdAstra – A stylish boutique hotel with Florence’s largest private garden.
- Hotel Lungarno – Overlooking the Arno River, this luxurious hotel is owned by the Ferragamo family.
- Genteel Home Piazza Pitti – apartments with private bedrooms and kitchen

Santa Croce – Best for Nightlife & Foodies
If you want to be close to all the major attractions but with a more local, lively atmosphere, Santa Croce is a fantastic choice. This area is full of authentic trattorias, wine bars, and local markets, making it a dream for food lovers. At night, the neighborhood comes alive with a mix of locals and visitors enjoying the bars and restaurants.
The best part? You’re still within walking distance of the historic center, but you’ll get a more authentic Florence experience.
Top Hotels in Santa Croce:
- La Maison du Sage – A charming boutique stay with elegant rooms.
- Plaza Hotel Lucchesi – A classic hotel with a rooftop pool offering stunning city views.
- The Sonetto powered by Sonder – A budget-friendly option in a great location

Santa Maria Novella – Best for Convenience & Budget-Friendly Options
If you’re arriving by train or planning to do day trips to places like Pisa, Siena, or Cinque Terre, staying near Santa Maria Novella is super convenient. It’s right by Florence’s main train station, meaning you can get around easily without dragging your luggage too far.
The area has cheaper hotels compared to the historic center, and while it’s not the prettiest part of Florence, it’s still within a 10-15 minute walk of major attractions. If you’re visiting on a budget but don’t want to stay too far from the action, this is a great option!
Top Hotels in Santa Maria Novella:
- The Place Firenze – A luxurious yet intimate hotel just minutes from the train station.
- c-hotels Ambasciatori – A stylish, mid-range hotel with great transport links.
- B&B La Residenza Dell’Orafo – A budget-friendly stay with great reviews.

San Lorenzo & San Marco – Best for Budget Travelers
If you’re looking for the best area to stay in Florence on a budget, San Lorenzo and San Marco are great options. These neighborhoods have a more residential feel, meaning fewer crowds and cheaper accommodation, while still being within a 15-minute walk of the historic center.
San Lorenzo is famous for its Mercato Centrale, where you can find delicious, affordable food (seriously, the fresh pasta and panini here are amazing!). Meanwhile, San Marco is home to Galleria dell’Accademia, where you can see Michelangelo’s David.
Top Hotels in San Lorenzo & San Marco:
- Loggiato dei Serviti – A historic hotel with lots of charm, close to Galleria dell’Accademia.
- Palazzo Castri 1874 – A stylish yet affordable hotel with a gorgeous garden.
- Plus Florence – A budget-friendly hostel with a pool and rooftop terrace.

Planning a trip to Tuscany? Check out my 3-day itinerary to explore the best of this stunning region, from historic towns to delicious local cuisine. Perfect for first-timers and seasoned travelers alike! Read more here: Tuscany in 3 Days
No matter where you stay, Florence will captivate you with its beauty, history, and charm. If you love being in the heart of the action, Centro Storico is your best bet. If you prefer local vibes and fewer tourists, Oltrarno or Santa Croce might be a better fit. And if you’re on a budget, San Lorenzo and Santa Maria Novella have some fantastic finds.
Have you been to Florence before? Which neighborhood was your favorite? Let me know in the comments! And if you found this guide helpful, don’t forget to save or share it for later.